Cost-Effectiveness of Risk-Based Colorectal Cancer Screening Strategies

Abstract

Population-based colorectal cancer screening programs place a substantial burden on healthcare systems. This health economic analysis compared standard age-based screening with personalized risk-based strategies incorporating genetic and lifestyle factors. Risk-based screening demonstrated improved cost-effectiveness by optimizing colonoscopy utilization while maintaining high cancer detection rates. These findings support the adoption of personalized screening approaches to enhance efficiency and sustainability of colorectal cancer prevention programs.