Long-Term Impact of Helicobacter pylori Eradication on Gastric Cancer Risk

Abstract

Helicobacter pylori infection is a well-established risk factor for gastric cancer. This prospective cohort study assessed the long-term impact of H. pylori eradication on gastric cancer incidence in a Korean population. A total of 2,100 infected individuals were followed for up to ten years after eradication therapy. Successful eradication was associated with a significant reduction in gastric cancer risk, particularly among younger patients and those without pre-existing atrophic gastritis. The results support population-based eradication strategies as an effective measure for gastric cancer prevention.